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Pipeline D - Motor disorders

Analysis of deficits related to motor and neurodegenerative diseases

  • SHIRPA – primary observation protocol for overall appearance
  • Grip strength – muscle function
  • Rotarod – basic motor coordination and balance
  • Beam Walk - coordination and balance deficits on beams of different diameters
  • Ladder Walk – motor coordination and grasping skills
  • Vertical Pole –striatal function; deficits are related to neurodegenerative diseases
  • Inverted grid – muscle strength related to weight bearing
  • Gait analysis – automated analysis of treadmill walking pattern by Digigait (Mousespecifics, Boston, USA) OR
  • Gait analysis – automated analysis of spontaneous gait using the CatWalk system (Noldus, Wageningen, The Netherlands); deficits are related to motor and neurodegenerative diseases