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GMC - German Mouse Clinic

GMC

German Mouse Clinic

GMC - German Mouse Clinic

GMC

German Mouse Clinic

04.02.2019

Sea squirt alternative oxidase prevents lethal mitochondrial cardiomyopathy in a mouse model of GRACILE syndrome

Scientists from the Folkhälsan Research Center in Helsinki, Finland, the German Mouse Clinic and colleagues from Sweden investigated, whether the...

18.12.2018

Cataract causing mutations in the betaB2 crystallin led to schizophrenia phenotypes in mice

The beta crystallin gene (CRYBB2) is an ocular structural gene and mutation in this gene can cause cataract. Interestingly, beyond its role in the eye...

25.09.2018

Zika virus infection: New insights into the impact of the Zika epidemic on the next generation

Scientists from the Heinrich-Pette-Institute Hamburg and the University of Veterinary Medicine Hannover in collaboration with the German Mouse Clinic...

12.06.2018

Common environmental enrichment devices for laboratory mice did not compromise data validity or comparability

To unravel whether environmental enrichment leads to a higher variation of results, scientists of the Helmholtz Zentrum München investigated the...

27.02.2018

Study unravel intergenerational effects of advanced paternal age on aging traits in offspring mice

Advanced age is a risk factor for many age related disorders, and it may enhance susceptibility for disease in the next generation. The recent joint...

Phenotype your mouse model

GMC I: 

  1. Systemic, comprehensive phenotyping in 14 different disease areas
  2. Customized primary phenotypic screening in specific areas of interest (e.g. behavior, neurology and neuropathology)

GMC II: 

  1. Hypothesis-driven phenotypic analysis using environmental challenges
  2. Combining environmental challenges

GMCIII:

  1. Systemic analysis of compounds and drugs

View results of mutant lines

View the results of mutant mouse lines in the GMC phenomap.

How primary mouse phenotyping leads to novel insights for human health

Mouse phenotyping helps to better understand human diseases. Read more how systemic primary screening of mouse mutants uncovers unexpected new gene functions.

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The GMC Consortium

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