Technologies of the allergy screen
We routinely investigate the impact of genetic modification in a murine ovalbumin model of allergic asthma to define the effect on the onset of the allergic phenotypic characteristics like e.g., eosinohils in the bronchoalveolar lavage fluid, Th2 cytokine and allergen-specific IgE production. Following allergic sensitization with the allergen, mice are exposed to allergen aerosol challenge followed by high-throughput measurement of multiple humoral and cellular parameters typically seen in association with the allergic response in the lung.
The Allergy screen in closely collaborating with the Immunology screen. Both are equipped whit up-to-date bench top equipment in order to get the maximal performance for the analysis of a large scale of trials using small volume of samples.
Tel. +49 89 3187-3656
Fax +49 89 3187-3661
Prof. Dr. med. Markus Ollert
Department of Infection and Immunity, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg
Department of Dermatology and Allergy Center, Odense Research Center for Anaphylaxis, University of Southern Denmark, Odense, Denmark
Prof. Dr. rer. nat. Carsten B. Schmidt-Weber Center of Allergy & Environment (ZAUM)Technische Universität München (TUM) and Helmholtz Center Munich